Article Abstract

Probiotics for prevention of necrotizing enterocolitis—where do we stand in 2017?

Authors: Joan L. Robinson


Necrotizing enterocolitis (NEC) affects primarily preterm infants and can lead to the devastating outcomes of intestinal failure secondary to resection of extensive necrotic bowel or death. A disordered intestinal microbiome is thought to be a risk factor for NEC. Probiotics are live microorganisms administered as food supplements or as pharmaceuticals in an attempt to improve human health. If the intestine of a preterm infant could be deliberately colonized with non-pathogenic organisms administered as a probiotic, the risk of NEC may decrease (1).