Article Abstract

Serum extracellular vesicles—a promising path towards an individualized medicine in primary sclerosing cholangitis and related cholangiocarcinoma

Authors: Torsten Schröder, Christian Sina

Abstract

Primary sclerosing cholangitis (PSC) is a chronic inflammatory disease of the biliary tract system, whose mechanisms of pathogenesis remain elusive. Most importantly, PSC is considered a major medical burden due to its premalignant nature (1). Malignant complications in PSC frequently occur within the hepatobiliary system, arising predominately as cholangiocarcinoma (CCC) (2).

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