Pediatric reference intervals for liver markers derived from healthy community-based subjects will improve diagnostic interpretation in children and adolescents

Anders Larsson, Peter Ridefelt


The article “New pediatric percentiles of liver enzyme serum levels (ALT, AST, GGT): effects of age, sex, BMI and pubertal stage” by Dr. Bussler et al. (1) is a major advancement, and a good example of the development in pediatric reference intervals that has occurred over the last 5 years.