%0 Journal Article %T PAFIYAMA syndrome: prevention is better than cure %A Perez-Quilis, Carme %A Lippi, Giuseppe %A Mena, Salva %A Löllgen, Herbert %A García-Giménez, José Luis %A Sanchis-Gomar, Fabian %J Journal of Laboratory and Precision Medicine %D 2016 %B 2016 %9 %! PAFIYAMA syndrome: prevention is better than cure %K %X We have recently purposed the definition of a new syndrome: strenuous endurance exercise-related atrial fibrillation (AF) under the acronym of ‘PAFIYAMA’ (‘paroxysmal AF in young and middle-aged athletes’). This syndrome may be the consequence, at least in part, of atrial fibrotic remodeling [increased left atrial (LA) size]. Although the management of this syndrome has deeply discussed, prevention is still in embryo. A number of circulation biomarkers, including proteins, cytokines and microRNA (miRNA) have been associated with cardiac adaptations to strenuous training and fibrosis. In particular, due to their involvement in a wide array of cardiac pathways under both physiological and pathological conditions, miRNA are deeply involved in cardiac biology, so that %U https://jlpm.amegroups.org/article/view/3589 %V 1 %P %@ 2519-9005