TY - JOUR AU - Jenks, Jeffrey Daniel AU - Hoenigl, Martin PY - 2018 TI - CD4:CD8 ratio and CD8+ cell count for prognosticating mortality in HIV-infected patients on antiretroviral therapy JF - Journal of Laboratory and Precision Medicine; Vol 3 (February 2018): Journal of Laboratory and Precision Medicine Y2 - 2018 KW - N2 - In people living with HIV (PLWH), immune compromise is largely due to a decrease in CD4 + T-lymphocyte (CD4) cells, resulting in increased rates of human immunodeficiency virus (HIV)-associated morbidity and mortality as CD4 + cell count declines. Previously, it was common to defer initiation of antiretroviral therapy (ART) in asymptomatic PLWH until their CD4 + cell count declined below a certain threshold, which has changed throughout the years based on updated guidelines, increasing access to ART, and lower drug prices. UR - https://jlpm.amegroups.org/article/view/3988