%0 Journal Article %T Are microRNA useful to predict prognosis in acute heart failure? %A Limongelli, Giuseppe %A Caiazza, Martina %A Masarone, Daniele %J Journal of Laboratory and Precision Medicine %D 2018 %B 2018 %9 %! Are microRNA useful to predict prognosis in acute heart failure? %K %X Acute heart failure (AHF) is a major cause of hospital admission in patients over 65 years of age (1). Despite improvements in the pharmacologic therapy, clinical outcome remain poor with 1-year mortality rates that reach 20–30% (2). The progression of HF is linked to numerous genetic and epigenetic factors (3), including small regions of highly conserved non-coding RNAs, called microRNAs (miRNAs), that are important regulators of gene expression and modulate numerous processes implied in the pathophysiology of HF (4,5). %U https://jlpm.amegroups.org/article/view/3996 %V 3 %P %@ 2519-9005