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Diagnostic performance of protein induced by vitamin K absence II for chronic hepatitis B-related hepatocellular carcinoma

  
@article{JLPM4931,
	author = {Jianxin Wan and Jiachun Su and Zhuangjian Ye and Chumei Huang and Jianbo Liang and Min Liu and Jinmei Luo and Laisheng Li},
	title = {Diagnostic performance of protein induced by vitamin K absence II for chronic hepatitis B-related hepatocellular carcinoma},
	journal = {Journal of Laboratory and Precision Medicine},
	volume = {4},
	number = {0},
	year = {2019},
	keywords = {},
	abstract = {Background: The aim of this study was to assess the diagnostic value of prothrombin induced by vitamin K absence-II (PIVKA-II) for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) in a Chinese population. 
Methods: In this study, receiver operating characteristics (ROC) curve was plotted, and the area under the ROC curve (AUC) was calculated to assess the diagnostic performance of serum PIVKA-II levels for HBV-related HCC (n=134) with negative or mildly elevated α-fetoprotein (AFP) relative to chronic hepatitis B (CHB, n=119) patients or healthy controls (n=100). 
Results: Serum levels of PIVKA-II were significantly greater in the HBV-related HCC patients compared to the CHB patients (P},
	issn = {2519-9005},	url = {https://jlpm.amegroups.org/article/view/4931}
}